Hemorrhagic complications of thrombolytic therapy

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Hemorrhagic complications of thrombolytic therapy.

Thrombolytic therapy salvages ischemic myocardium by rapidly reestablishing coronary artery patency in acute myocardial infarction. One of its major limitations is the complication of hemorrhage. A retrospective study of myocardial infarction patients who received thrombolytic therapy was performed to determine risk factors associated with a hemorrhagic event. Three hundred fifty patients were ...

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Hemorrhagic complications of thrombolytic therapy in experimental stroke.

Recent success with thrombolytic therapy for acute myocardial infarction has stimulated interest in its use for stroke. To determine the hemorrhagic potential of thrombolytic therapy in experimental cerebral infarction, we compared a group of tissue plasminogen activator-treated rabbits (n = 4) with 2 groups of streptokinase-treated rabbits (n = 6 in each), as well as with 3 groups of heparin-t...

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Hemorrhagic complications of anticoagulant treatment: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

This chapter about hemorrhagic complications of anticoagulant treatment is part of the seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Bleeding is the major complication of anticoagulant therapy. The criteria for defining the severity of bleeding varies considerably between studies, accounting in part for the variation in the rates of bleeding repo...

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Hemorrhagic complications of long-term anticoagulant therapy.

T he main complication of anticoagulation therapy is bleeding. We have conducted a literature review to determine: (a) the rate of bleeding during long-term anticoagulant therapy in various clinical disorders, and (b) the clinical and laboratory risk factors that predispose patients to bleeding. For the purposes of this review, we defined long-term therapy as lasting greater than 4 weeks. Hemor...

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Race/Ethnic differences in the risk of hemorrhagic complications among patients with ischemic stroke receiving thrombolytic therapy.

BACKGROUND AND PURPOSE Race/ethnic-related differences in safety of intravenous thrombolytic therapy have been shown in patients with myocardial infarction, but not studied in ischemic stroke. METHODS Using data from the Get With The Guidelines (GWTG)-Stroke program (n=54 334), we evaluated differences in risk-adjusted bleeding rates (any, symptomatic intracerebral hemorrhage [sICH], serious ...

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ژورنال

عنوان ژورنال: Medicinski pregled

سال: 2012

ISSN: 0025-8105,1820-7383

DOI: 10.2298/mpns1202009v